P-753 Preferences in subfertile women for hysterosalpingography or transvaginal hydrolaparoscopy in the fertility work-up: a labelled discrete choice experiment.

Abstract Study question What aspects do subfertile women prefer for hysterosalpingography (HSG) or transvaginal hydrolaparoscopy (THL) to assess their Fallopian tubes? Summary answer The chance of a false negative result, failure rate, and waiting time are attributes that impact women’s preference tubal patency testing strategy. is known already THL HSG commonly used diagnostic tests testing, both with different features. radiological procedure whit contrast evaluate patency, whereas where access the pouch Douglas obtained an endoscope tubes tested methylene blue. was found non-inferior as first-line test in terms conception leading live birth. Until now, limited research has been performed study values preferences work-up. design, size, duration We conducted labelled discrete choice experiment (DCE), which attribute-based survey method measuring preferences. This DCE consisted 2 questionnaires each 12 sets. Women indication were included between September 2021 January 2023 two Dutch hospitals. They randomly assigned questionnaire 1 2. Participants/materials, setting, methods Attributes defined based on literature review, structured patient interviews expert focus groups. resulted five final attributes: having “false negative” complication subsequent management after failed time. asked choose sets hypothetical scenarios levels attributes. Data analysed by using multinomial logistic regression. Main results role returned 75 out 80 women. Mean age 31.8 years mean subfertility 23.5 months. 65 experienced primary vs 10 who secondary subfertility. For preferred lower result (p < 0.001), rate = 0.008) shorter 0.003). Outcomes complications not significant. Only group subfertility, if conclusive there reach Douglas, have conventional laparoscopy over expectant 0.01). choosing 0.02) 0.001). Because design we performed, saw chose significantly more than HSG; 83% 17% (P 0.03). may be caused way counselling fact these medical centres one few Netherlands perform THL. Limitations, reasons caution Our analysis 78 women, showed significant outcomes specific attributes, but it possible would stronger associations larger sample size. Wider implications findings These provide insight perspective about fertility work-up they enable informed decision making. Further needed compare our other forms Trial registration number N20.009